The objective of this study was to investigate the risk factors and diagnosis measure of COVID-19-associated pulmonary aspergillosis (CAPA). This study included 201 COVID-19 patients from December 1, 2022, to January 31, 2023; 7 (3.5%) were diagnosed with CAPA. The main risk factors were age, MV, ICU admission and COPD, and the presence of comorbidities such as ARDS and hypoproteinemia in COVID-19 patients, more susceptible to Aspergillus infection. In addition to specimen culture in the lower respiratory tract, the 1,3-beta-D-glucan antigen test can serve as an important screening indicator for early CAPA diagnosis in non-granulocytopenia patients.
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Sakarya Univ, Training & Res Hosp, Dept Pediat, Sakarya, TurkeySakarya Univ, Training & Res Hosp, Dept Pediat, Sakarya, Turkey
Seker, Elif
Ozdemir, Oner
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Sakarya Univ, Training & Res Hosp, Dept Pediat, Div Allergy & Immunol, Sakarya, TurkeySakarya Univ, Training & Res Hosp, Dept Pediat, Sakarya, Turkey
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SEPAR, TB Res Programme PII TB, Barcelona, SpainAlma Mater Studiorum Univ Bologna, Dept Med & Surg Sci, Infect Dis Unit, Bologna, Italy
Garcia-Garcia, Jose-Maria
Blanc, Francois-Xavier
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Ctr Hosp Univ, Nantes, FranceAlma Mater Studiorum Univ Bologna, Dept Med & Surg Sci, Infect Dis Unit, Bologna, Italy
Blanc, Francois-Xavier
Borisov, Sergey
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Moscow Res & Clin Ctr TB Control, Moscow, RussiaAlma Mater Studiorum Univ Bologna, Dept Med & Surg Sci, Infect Dis Unit, Bologna, Italy
Borisov, Sergey
Goletti, Delia
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IRCCS, Translat Res Unit, Natl Inst Infect Dis L Spallanzani, Rome, ItalyAlma Mater Studiorum Univ Bologna, Dept Med & Surg Sci, Infect Dis Unit, Bologna, Italy
Goletti, Delia
Motta, Ilaria
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Osped Amedeo Savoia, Clin Univ Malattie Infett, Dipartimento Sci Med, Turin, ItalyAlma Mater Studiorum Univ Bologna, Dept Med & Surg Sci, Infect Dis Unit, Bologna, Italy
Motta, Ilaria
Codecasa, Luigi Ruffo
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Osped Niguarda Ca Granda, Villa Marelli Inst, TB Reference Ctr, Milan, ItalyAlma Mater Studiorum Univ Bologna, Dept Med & Surg Sci, Infect Dis Unit, Bologna, Italy
Codecasa, Luigi Ruffo
Tiberi, Simon
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Queen Mary Univ London, Barts & London Sch Med & Dent, Blizard Inst, London, England
Barts Hlth NHS Trust, Royal London Hosp, Div Infect, London, EnglandAlma Mater Studiorum Univ Bologna, Dept Med & Surg Sci, Infect Dis Unit, Bologna, Italy
Tiberi, Simon
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Sotgiu, Giovanni
Migliori, Giovanni Battista
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Ist Clin Sci Maugeri IRCCS, Serv Epidemiol Clin Malattie Resp, Via Roncaccio 16, I-21049 Tradate, ItalyAlma Mater Studiorum Univ Bologna, Dept Med & Surg Sci, Infect Dis Unit, Bologna, Italy
机构:
Appalachian Reg Healthcare Internal Med Residency, Whitesburg, KY USAAppalachian Reg Healthcare Internal Med Residency, Whitesburg, KY USA
Bhopalwala, Huzefa
Mishra, Vinayak
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Grant Govt Med Coll, Mumbai, Maharashtra, India
Sir JJ Grp Hosp, Mumbai, Maharashtra, IndiaAppalachian Reg Healthcare Internal Med Residency, Whitesburg, KY USA
Mishra, Vinayak
Do, Tuong Vi
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机构:
Appalachian Reg Healthcare Internal Med Residency, 81 Ball Pk Rd, Harlan, KY 40831 USAAppalachian Reg Healthcare Internal Med Residency, Whitesburg, KY USA
Do, Tuong Vi
Gudipati, Mythili
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机构:
Appalachian Reg Healthcare Internal Med Residency, 81 Ball Pk Rd, Harlan, KY 40831 USAAppalachian Reg Healthcare Internal Med Residency, Whitesburg, KY USA
Gudipati, Mythili
Ganti, Subramanya Shyam
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机构:
Appalachian Reg Healthcare Internal Med Residency, 81 Ball Pk Rd, Harlan, KY 40831 USAAppalachian Reg Healthcare Internal Med Residency, Whitesburg, KY USA
Ganti, Subramanya Shyam
JOURNAL OF INVESTIGATIVE MEDICINE HIGH IMPACT CASE REPORTS,
2022,
10