B cells! Don't go the wrong way in this tumor

被引：0

作者：

Pupier, Guilhem ^{[1
]}

Sautes-Fridman, Catherine ^{[1
]}

机构：

[1] Sorbonne Univ, Univ Paris Cite, Ctr Rech Cordeliers, INSERM,Equipe Labellisee Ligue Natl Contre Canc,US, Paris, France

来源：

IMMUNITY | 2024年 / 57卷 / 07期

关键词：

IMMUNITY;

D O I：

10.1016/j.immuni.2024.06.007

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The association of tertiary lymphoid structures (TLSs) with survival and immunotherapy response brought B cells to center stage. In a pan-cancer B cells atlas in Science, Ma et al. show that germinal center reaction generating anti-tumor antibody-secreting cells (ASCs) from B memory cells in mature TLSs co-exist in tumors with extra-follicular reaction generating auto-reactive ASCs from memory B cells in immature TLSs.

引用

页码：1454 / 1456

页数：3

共 50 条

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