Visible-light-mediated C-H amidation of imidazoheterocycles with N-amidopyridiniums

被引:3
|
作者
Wen, Lili [1 ]
Tan, Qiannan [1 ]
Pi, Chao [2 ,3 ]
Yuan, Juan [1 ]
Zhang, Jingyu [1 ]
Mi, Xia [1 ]
机构
[1] Henan Univ Chinese Med, Coll Pharm, Zhengzhou 450046, Peoples R China
[2] Zhengzhou Univ, Green Catalysis Ctr, Key Lab Appl Chem Henan Univ, Henan Key Lab Chem Biol & Organ Chem, Zhengzhou 450052, Peoples R China
[3] Zhengzhou Univ, Coll Chem, Zhengzhou 450052, Peoples R China
基金
中国国家自然科学基金;
关键词
IMIDAZOPYRIDINES; INHIBITORS; PRECURSORS; AMINATION; PROGRESS; AGENTS; SALTS;
D O I
10.1039/d4ob00461b
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
C-3 amidated imidazoheterocycles were synthesized via a visible light-promoted reaction of imidazoheterocycles with N-amidopyridinium salts catalyzed by 4CzIPN under mild conditions. For imidazoheterocycles and N-amidopyridinium salts with various substituents, the reaction proceeded smoothly to give the corresponding products in moderate to good yields. The reaction provides a new strategy for the synthesis of secondary amides with the imidazo[1,2-a]pyridine core.
引用
收藏
页码:4647 / 4650
页数:4
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