Chemokine Receptor 4-Targeted PET/CT With 68Ga-Pentixather Detects More Lesions Than 68Ga-Pentixafor PET/CT in Multiple Myeloma

被引：2

作者：

Yang, Qiao ^{[1
]}

Zhang, Fujing ^{[2
]}

Hao, Zhixin ^{[1
]}

Zhuang, Junling ^{[2
,3
]}

Huo, Li ^{[1
]}

机构：

[1] Chinese Acad Med Sci & Peking Union Med Coll, Beijing Key Lab Mol Targeted Diag & Therapy Nucl, Peking Union Med Coll Hosp,Ctr Rare Dis Res, Dept Nucl Med,State Key Lab Complex Severe & Rare, 1 Shuaifuyuan, Beijing 100730, Peoples R China

[2] Peking Union Med Coll & Chinese Acad Med Sci, Peking Union Med Coll Hosp, Dept Hematol, Beijing, Peoples R China

[3] Peking Union Med Coll Hosp, Dept Hematol, 1 Shuaifuyuan, Beijing 100730, Peoples R China

来源：

CLINICAL NUCLEAR MEDICINE | 2024年 / 49卷 / 06期

基金：

中国国家自然科学基金;

关键词：

Ga-68-pentixather; multiple myeloma; PET/CT; CXCR4-DIRECTED ENDORADIOTHERAPY;

D O I：

10.1097/RLU.0000000000005194

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

An 83-year-old woman with newly diagnosed multiple myeloma (MM) was enrolled in our Ga-68-pentixather and Ga-68-pentixafor PET/CT trial for evaluation of tumor burden. Ga-68-pentixather PET/CT detected more focal bone lesions, and the uptake levels of focal bone lesions on Ga-68-pentixather PET/CT were higher than those on Ga-68-pentixafor PET/CT. This suggests that Ga-68-pentixather PET/CT may be an alternative imaging modality and more sensitive in detecting MM lesions than Ga-68-pentixafor PET/CT.

引用

页码：592 / 593

页数：2

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