IgA multiple myeloma-associated mediastinal spinal plasmacytoma presenting as spinal cord compression

被引:0
|
作者
Prathivadhi-Bhayankaram, Sruti [1 ]
Marar, Rosalyn [2 ]
Atiya, Samir [2 ]
Krishnan, Mridula [2 ]
机构
[1] Univ Iowa Hosp & Clin, Internal Med, Iowa City, IA 52242 USA
[2] Univ Nebraska Med Ctr, Omaha, NE USA
关键词
Oncology; End of life decisions (palliative care); Radiotherapy; EXTRAMEDULLARY PLASMACYTOMA;
D O I
10.1136/bcr-2023-257026
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Multiple myeloma associated with extramedullary plasmacytoma at initial presentation is rare. We describe a case of a man in his 30s who initially presented with symptoms of spinal cord compression. Further imaging revealed a mediastinal tumour, with a biopsy confirming plasmacytoma. Immunofixation revealed IgA lambda paraprotein. Bone marrow biopsy demonstrated atypical T-cell cytotoxic proliferation and trilineage hypoplasia. The patient was diagnosed with extramedullary plasmacytoma with active IgA multiple myeloma. The patient received mediastinal radiation to the tumour, followed by anti-myeloma therapy. This diagnosis is critical as managing a solitary plasmacytoma drastically differs from an extramedullary plasmacytoma with active multiple myeloma.
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页数:4
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