Ecosystem ecology is the core content of ecosystem science in the Institute of Geographic Sciences and Natural Resources Research, Chinese Academy of Sciences (IGNSRR). Our first mission is to develop techniques and methods of ecosystem monitoring and simulation, by which we explore the theories and pathways in solving eco-environmental issues at regional scales. Second, we monitor ecosystem changes, identify the dynamics and patterns, and advance the discipline developments of ecosystem ecology, biogeography ecology, global change ecology, and eco-informatics. Third, we serve for the national and regional ecological constructions by addressing issues related to global changes and regional sustainable developments. To meet national needs, we synthesize and innovate technique and modes of ecosystem management for typical regions of China, i.e. agricultural regions of northern China, hilly red soil forestry regions of southern China, agricultural and pastoral regions of the Tibetan Plateau and Loess Plateau. Utilizing these innovated management modes, we aim to solve fundamental problems in ecological construction and adapt to global changes, and facilitate science advance in regional ecosystem management. Our research directions comprise the following five fields: (1) network monitoring, simulation and ecosystem data management; (2) ecosystem structure, process and function; (3) ecosystem pattern and the underlying mechanism; (4) ecosystem responses and adaptation to global change; (5) ecosystem management and ecosystem services. Centered around the above five foci research directions, we systematically explore theories of ecosystem ecology and their applications, through which we position our research in frontier lines of China and the world. © 2020, Science Press. All right reserved.