Improving the predictive power of mouse models

被引：0

作者：

Pera, Martin ^{[1
]}

Greene, Andy ^{[1
]}

Cardon, Lon ^{[1
]}

Carter, Gregory W. ^{[1
]}

Chesler, Elissa J. ^{[1
]}

Churchill, Gary ^{[1
]}

Kumar, Vivek ^{[1
]}

Lutz, Cathleen ^{[1
]}

Munger, Steven ^{[1
]}

Murray, Steve ^{[1
]}

O'Connell, Kristen ^{[1
]}

Reinholdt, Laura ^{[1
]}

Rosenthal, Nadia A. ^{[1
,2
]}

机构：

[1] Jackson Lab, Bar Harbor, ME 04609 USA

[2] Imperial Coll London, Imperial Ctr Translat & Expt Med, Natl Heart & Lung Inst, London, England

来源：

NATURE BIOTECHNOLOGY | 2024年 / 42卷 / 08期

关键词：

SYSTEMS GENETICS;

D O I：

10.1038/s41587-024-02349-2

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Comparative studies that integrate genetically diverse mouse models and in vitro cell-based assays will accelerate drug discovery for precision medicine.

引用

页码：1175 / 1177

页数：3

共 50 条

[1] Improving the predictive power of microkinetic models via machine learning
Rangarajan, Srinivas
Tian, Huijie
CURRENT OPINION IN CHEMICAL ENGINEERING, 2022, 38
[2] Improving mouse models
Sarah Seton-Rogers
Nature Reviews Cancer, 2013, 13 (5) : 295 - 295
[3] Multiple-Swarm Ensembles: Improving the Predictive Power and Robustness of Predictive Models and Its Use in Computational Biology
Alves, Pedro
Liu, Shuang
Wang, Daifeng
Gerstein, Mark
IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 2018, 15 (03) : 926 - 933
[4] Improving the predictive quality of CoMFA models
Kroemer, RT
Hecht, P
Guessregen, S
Liedl, KR
PERSPECTIVES IN DRUG DISCOVERY AND DESIGN, 1998, 12 : 41 - 56
[5] Improving the Predictive Accuracy of Hurricane Power Outage Forecasts Using Generalized Additive Models
Han, Seung-Ryong
Guikema, Seth D.
Quiring, Steven M.
RISK ANALYSIS, 2009, 29 (10) : 1443 - 1453
[6] Improving the predictive power of spatial statistical models of stream macroinvertebrates using weighted autocovariance functions
Frieden, Jennifer C.
Peterson, Erin E.
Webb, J. Angus
Negus, Peter M.
ENVIRONMENTAL MODELLING & SOFTWARE, 2014, 60 : 320 - 330
[7] Improving the interpretability and predictive power of hydrological models: Applications for daily streamflow in managed and unmanaged catchments
Bhasme, Pravin
Bhatia, Udit
JOURNAL OF HYDROLOGY, 2024, 628
[8] Improving Predictive Models for Noncycloplegic Binocular Autorefractors
Patil, Thayjas
Sharma, Pranav
Modjesky, Heather
Silbert, David
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2023, 64 (08)
[9] Boosting predictive power of QSAR models
Fourches, Denis
Muratov, Eugene
Pu, Dongqiuye
Tropsha, Alexander
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2011, 241
[10] Predictive Power of “A Minima” Models in Biology
L. Almeida
J. Demongeot
Acta Biotheoretica, 2012, 60 : 3 - 19

← 1 2 3 4 5 →