Maternal Preconception Serum Alanine Aminotransferase Levels and Risk of Preterm Birth among Reproductive-Aged Women - China, 2013-2017

被引：1
|
作者：
Zhao, Chuanyu [1 ,2 ,3 ]
Jia, Jiajing [4 ]
Wu, Hanbin [1 ,2 ]
Xu, Qin [1 ,2 ]
Lyu, Xinyi [1 ,2 ,3 ]
Liu, Meiya [1 ,2 ]
Hu, Xuan [1 ,2 ]
Lei, Jueming [1 ,2 ]
Deng, Yuzhi [1 ,2 ]
He, Yuan [1 ,2 ,3 ]
Wang, Yuanyuan [1 ,2 ,3 ]
Peng, Zuoqi [1 ,2 ]
Zhang, Ya [1 ,2 ]
Zhang, Hongguang [1 ,2 ]
Wang, Qiaomei [1 ,2 ]
Shen, Haiping [1 ,2 ]
Zhang, Yiping [1 ,2 ]
Yan, Donghai [1 ,2 ]
Yang, Ying [1 ,2 ]
Ma, Xu [1 ,2 ,3 ]
机构：
[1] Natl Res Inst Family Planning, Beijing, Peoples R China
[2] Natl Human Genet Resources Ctr, Beijing, Peoples R China
[3] Peking Union Med Coll, Grad Sch, Beijing, Peoples R China
[4] Chinese Acad Med Sci & Peking Union Med Coll, Fuwai Hosp, Natl Ctr Cardiovasc Dis, Dept Epidemiol, Beijing, Peoples R China
来源：
CHINA CDC WEEKLY | 2024年 / 6卷 / 10期
关键词：
FATTY LIVER-DISEASE; ASSOCIATION; PREGNANCY; MORTALITY;
D O I：
10.46234/ccdcw2024.037
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
What is already known about this topic? The significance of maternal liver health concerning preterm birth (PTB) is well recognized; however, there is a gap in understanding the precise influence of preconception serum alanine aminotransferase (ALT) levels on the risk of PTB. What is added by this report? In this retrospective cohort study, a J -shaped relationship between preconception serum ALT levels and risk of PTB was observed, indicating that both significantly elevated and decreased ALT levels may contribute to the risk. What are the implications for public health practice? Maintaining optimal preconception serum ALT levels may reduce the risk of PTB, thereby informing specific preventive measures for women of reproductive age.
引用
收藏
页码：181 / 188
页数：9
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