APOE4 homozygosity is a new genetic form of Alzheimer's disease

被引：0
|
作者：
Xu, Qin [1 ,2 ]
Liang, Zherui [1 ,3 ]
Huang, Yadong [1 ,2 ,3 ,4 ,5 ]
机构：
[1] Gladstone Inst, Gladstone Inst Neurol Dis, San Francisco, CA 94158 USA
[2] Gladstone Inst, Gladstone Ctr Translat Advancement, San Francisco, CA 94158 USA
[3] Univ Calif San Francisco, Neurosci Grad Program, San Francisco, CA 94143 USA
[4] Univ Calif San Francisco, Dept Neurol, San Francisco, CA 94143 USA
[5] Univ Calif San Francisco, Dept Pathol, San Francisco, CA 94143 USA
来源：
NATURE MEDICINE | 2024年 / 30卷 / 05期
基金：
美国国家卫生研究院;
关键词：
D O I：
10.1038/s41591-024-02923-w
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
New data confirm that APOE4 homozygosity is a major genetic cause of Alzheimer's disease, warranting the development of specialized research strategies, treatment approaches and clinical trials.
引用
收藏
页数：15
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