Mechanisms of Mycobacterium tuberculosis Drug Resistance

被引：0
|
作者：
Shulgina, M. V. [1 ]
机构：
[1] Almazov Natl Med Res Ctr, Inst Med Educ, St Petersburg 197341, Russia
来源：
MOLECULAR GENETICS MICROBIOLOGY AND VIROLOGY | 2024年 / 39卷 / 01期
关键词：
Mycobacterium tuberculosis; multidrug resistance; mechanisms of action of antituberculosis drugs; mechanisms of drug resistance; PARA-AMINOSALICYLIC ACID; ETHAMBUTOL RESISTANCE; ANTIBIOTIC-RESISTANCE; MUTATIONS; NITROREDUCTASE; SUSCEPTIBILITY; DETERMINANTS; PYRAZINAMIDE; BEDAQUILINE; EVOLUTION;
D O I：
10.3103/S0891416824700010
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The review presents the results of investigations of the mechanisms of action of long-used and new antituberculosis drugs, and information about new chemical compounds as potential antituberculosis drugs. Data are given on mutations in a number of infectant genes associated with or leading to bacterial resistance to these drugs. The review comprises the results of 67 publications, systematic reviews, and electronic databases.
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页码：1 / 13
页数：13
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