Treatable cerebellar ataxias

被引:6
|
作者
Divya, K. P. [1 ]
Kishore, Asha [1 ]
机构
[1] Sree Chitra Tirunal Inst Med Sci & Technol, Dept Neurol, Trivandrum 695011, Kerala, India
关键词
Treatable ataxia; Cerebellar ataxia; Acute ataxia; Genetic ataxia; ACID DECARBOXYLASE ANTIBODIES; GLUT1 DEFICIENCY SYNDROME; MOVEMENT-DISORDERS; CEREBROTENDINOUS-XANTHOMATOSIS; DIETARY-TREATMENT; REFSUMS-DISEASE; DIAGNOSIS; SPECTRUM; HETEROGENEITY; DYSFUNCTION;
D O I
10.1016/j.prdoa.2020.100053
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Cerebellar ataxic syndrome is a heterogenous class of disorders which can result from a miscellany of causes-genetic or acquired. There are a few metabolic, immune mediated, inflammatory and hereditary causes of ataxia which can be diagnosed from the gamut of possibilities, offering great relief to the ailing patient, their family and the treating physician. A pragmatic algorithm for diagnosing treatable causes of ataxia includes a thorough clinical history, meticulous examination for associated signs and an investigative mind to clinch the diagnosis. With novel diagnostic techniques and targeted therapies, early diagnosis and treatment can lead to favourable outcomes. In this review, diseases presenting predominantly as cerebellar ataxia and are treatable by targeted therapies are discussed. (c) 2020 Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license (http:// creativecommons.org/licenses/by-nc-nd/4.0/).
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页数:7
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