Interventions for preventing or controlling health care-associated infection among health care workers or patients within primary care facilities: A scoping review

Background: This review aimed to synthesize the evidence on infection prevention and control interventions for the prevention of health care-associated infection among health care workers or patients within primary care facilities. Methods: PubMed, CINAHL, EMBASE, and CENTRAL databases were searched for quantitative studies published between 2011 and 2022. Study selection, data extraction, and quality assessment using Cochrane and Joanna Briggs tools, were conducted by independent review with additional sensitivity checking performed on study selection. Results: Four studies were included. A randomized trial and a cross-sectional survey, respectively, found no statistical difference in laboratory -confirmed influenza in health care workers wearing N95 versus medical masks ( P = .18) and a significant inverse association between the implementation of tuberculosis control measures and tuberculosis incidence ( P = .02). For the prevention of surgical site infections following minor surgery, randomized trials found nonsterile gloves (8.7%; 95% confidence interval, 4.9%-12.6%) to be noninferior to sterile gloves (9.3%; 95% confidence interval, 7.4%-11.1%) and no significant difference between prophylactic antibiotics compared to placebo ( P = .064). All studies had a high risk of bias. Conclusions: Evidence for infection prevention and control interventions for the prevention of health care-associated infection in primary care is very limited and insufficient to make practice recommendations. Nevertheless, the findings highlight the need for future research. (c) 2023 The Author(s). Published by Elsevier Inc. on behalf of Association for Professionals in Infection Control and Epidemiology, Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).