Advances in frontiers of organic synthesis in microreactor

被引：0
|
作者：
Zhang J. [1 ]
Zhou Y. [1 ]
Chen Z. [1 ]
Xu J. [1 ]
机构：
[1] Department of Chemical Engineering, State Key Laboratory of Chemical Engineering, Tsinghua University, Beijing
来源：
Huagong Xuebao/CIESC Journal | 2022年 / 73卷 / 08期
关键词：
hazardous reaction; intrinsic safety; microreactor; organic synthesis; strong exothermic;
D O I：
10.11949/0438-1157.20220403
中图分类号：
学科分类号：
摘要：
Microreactor generally refers to microreactor with characteristic size ranging from microns to hundreds of microns and is one of the core equipment of microchemical systems. Compared with the traditional tank reactor, microreactors show unique advantages in the synthesis process of dangerous or flammable and explosive products and in the rapid reaction process. Due to its excellent heat and mass transfer performance, the microreactor technology makes these hazardous chemical processes more accurate, efficient and safer. In this way, the microreactor has important industrial application value and is also one of the key development directions in the chemical industry. This paper mainly introduces the Hoffmann rearrangement, cycloaddition, diazotization and coupling, alkylation, nitrogen oxidation involved in the use of microreactor technology in the field of fine chemicals such as medicine, pesticide, dye and pigment in recent years. The research progress of typical“strong exothermic fast reaction”organic synthesis and its development prospects are prospected. © 2022 Materials China.
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页码：3472 / 3482
页数：10
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