BioBulkFoundary: a customized webserver for exploring biosynthetic potentials of bulk chemicals

被引:0
|
作者
Sun, Dandan [1 ]
Ding, Shaozhen [2 ]
Cai, Pengli [1 ]
Zhang, Dachuan [3 ]
Han, Mengying [1 ]
Hu, Qian-Nan [1 ]
机构
[1] Univ Chinese Acad Sci, Shanghai Inst Nutr & Hlth, Chinese Acad Sci, CAS Key Lab Computat Biol, Shanghai 200031, Peoples R China
[2] Wuhan LifeSynther Sci & Technol Co Ltd, Wuhan 430000, Peoples R China
[3] Swiss Fed Inst Technol, Inst Environm Engn, Ecol Syst Design, CH-8093 Zurich, Switzerland
关键词
PATHWAYS;
D O I
10.1093/bioinformatics/btac640
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Advances in metabolic engineering have boosted the production of bulk chemicals, resulting in tons of production volumes of some bulk chemicals with very low prices. A decrease in the production cost and overproduction of bulk chemicals makes it necessary and desirable to explore the potential to synthesize higher-value products from them. It is also useful and important for society to explore the use of design methods involving synthetic biology to increase the economic value of these bulk chemicals. Therefore, we developed 'BioBulkFoundary', which provides an elaborate analysis of the biosynthetic potential of bulk chemicals based on the state-of-art exploration of pathways to synthesize value-added chemicals, along with associated comprehensive technology and economic database into a user-friendly framework.
引用
收藏
页码:5137 / 5138
页数:2
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