Coherent Raman Scattering Microscopy Technique and Its Biomedical Applications

被引：0
|
作者：
Li Z. [1 ]
Li S. [1 ]
Zhang S. [1 ]
Shen B. [1 ]
Qu J. [1 ]
Liu L. [1 ]
机构：
[1] Key Laboratory of Optoelectronics Devices and Systems of Guangdong Province and Ministry of Education, College of Physics and Optoelectronic Engineering, Shenzhen University, Shenzhen, 518060, Guangdong
来源：
Zhongguo Jiguang/Chinese Journal of Lasers | 2020年 / 47卷 / 02期
关键词：
Biomedicine; Coherent anti-stokes Raman scattering; Coherent Raman scattering microscopy technique; Label-free imaging; Stimulated Raman scattering imaging;
D O I：
10.3788/CJL202047.0207005
中图分类号：
学科分类号：
摘要：
As a new imaging technique, coherent Raman scattering (CRS) microscopy has been widely used in chemical structure and composition analysis because of its advantages of label-free, high specificity, and on-invasion. In recent years, the mutual cross-over and integrated development of photonics, biomedicine, and microscopic imaging technology has greatly promoted the application of CRS microscopy in biomedicine. This paper briefly introduces the basic principle of CRS microscopy and its classification, then explains the most widely used implementation of CRS, and summarizes the recent applications of CRS microscopic imaging in biomedicine, including detection, lipid analysis, and protein conformation change. Finally, the future development of CRS is discussed. © 2020, Chinese Lasers Press. All right reserved.
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