Effect of Hemoglobin on the Prognosis of Patients With Advanced Cancer in Palliative Care Settings

被引:0
|
作者
Liao, Xinghe [1 ,2 ]
Bao, Cihang [2 ,3 ,4 ]
Song, Qi [5 ]
Liu, Hui [6 ]
Liu, Minghui [1 ,2 ]
Zhang, Zhe [1 ,2 ]
Zhang, Jin [1 ,2 ]
Zhang, Chenyue [1 ,2 ]
Zhao, Weiwei [1 ,2 ]
机构
[1] Fudan Univ, Shanghai Canc Ctr, Dept Integrated Therapy, Shanghai 20032, Peoples R China
[2] Fudan Univ, Shanghai Med Coll, Dept Oncol, Shanghai, Peoples R China
[3] Shanghai Proton & Heavy Ion Ctr, Dept Radiat Oncol, Shanghai, Peoples R China
[4] Shanghai Engn Res Ctr Proton & Heavy Ion Radiat Th, Shanghai, Peoples R China
[5] Nanchang Univ, Affiliated Hosp 1, Dept Med Oncol, Nanchang, Peoples R China
[6] Wuhan Univ, Renmin Hosp, Dept Neurol, Wuhan, Peoples R China
来源
PALLIATIVE MEDICINE REPORTS | 2024年 / 5卷 / 01期
基金
中国国家自然科学基金;
关键词
advanced cancer; hemoglobin; palliative care; prognostic value; ANEMIA; PREVALENCE; SURVIVAL; DISEASE;
D O I
10.1089/pmr.2023.0041
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
Background: Hemoglobin (Hb) has been reported as a prognostic factor in many cancer patients. However, its effect on the prognosis of patients with advanced cancer receiving palliative treatment is still unclear.Objective: The aim of this study was to assess whether Hb can be used as a prognostic indicator for patients with advanced cancer receiving palliative treatment.Methods: From July 2013 to October 2015, 368 consecutive patients were treated in the Palliative Treatment Center of Shanghai Cancer Center, Fudan University. The data of 105 patients were extended in the follow-up. The cutoff value selected for Hb was 100 g/L.Results: The median survival time of patients with low hemoglobin (LHb) was shorter than that of patients with high hemoglobin (HHb; 41 days vs. 84 days). In addition, in the follow-up readmission cohort (n = 105), the median survival time of patients with HHb (HHb -> HHb) was 3.44 times longer than that of patients with LHb (HHb -> LHb). To sum up, both LHb and descending Hb were identified as independent prognostic factors for poor prognosis.Conclusions: In palliative treatment, Hb can be used as a stratification factor to judge poor prognosis in advanced cancer patients.
引用
收藏
页码:177 / 184
页数:8
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