Midterm outcomes of one anastomosis gastric bypass for patients with BMI < 35 kg/m2 from a large single center

Background: One-anastomosis gastric bypass (OAGB) is gaining more attention in patients with severe obesity and recently is used for patients with body mass index (BMI) < 35 kg/m(2). In this 5-year single center experience we aim to report our outcomes of using OAGB for patients with BMI < 35 kg/m(2). Methods: This is a retrospective analysis of prospectively collected data recorded in to our national obesity registry database. Variables including age, sex, weight, BMI, any associated disease, blood levels of metabolic markers, nutrients, and vitamins before and after surgery were extracted and analyzed. Results: 173 patients with mean age and BMI of 41 +/- 10 years and 33 +/- 1 kg/m(2) underwent OAGB and at least one of the obesity-associated medical problems was found in 88 (50.5%) of them preoperatively. The mean duration of surgery and length of hospital stay were 60.7 +/- 7.4 min and 1.3 +/- 1.4 days. 78% and 70% of patients had available data at 24 and 60 months, respectively. The mean BMI was 23.9 +/- 2.2 kg/m(2) 1 year after surgery and each year after that till 5 years was 24 +/- 2, 24.4 +/- 2.6, 25.1 +/- 2.7, and 25.5 +/- 2.7 kg/m(2). Significant improvement in levels of fasting blood glucose, lipid profile, and liver enzymes were observed. Conclusion: OAGB for BMI < 35 kg/m(2) has significant effects in weight loss, helps remit diabetes and hypertension in the majority of cases, improves lipid profile, and has no increased burden of postoperative problems or deficiency in nutritional factors rather than what is known and predictable.