Light-Chain (AL) Cardiac Amyloidosis Presenting as Heart Failure With Reduced Ejection Fraction

被引：0
|
作者：
Santiago, Luis E. [1 ,2 ]
Alvi, Ali Tariq [1 ,2 ]
Melnychuk, Veniamin [1 ,2 ]
Mesquita, Philip [1 ,2 ]
Aneja, Pallavi [1 ,2 ]
机构：
[1] HCA Florida Northwest Hosp, Internal Med, Margate, FL 33324 USA
[2] HCA Florida Westside Hosp, Internal Med, Plantation, FL 33324 USA
来源：
CUREUS JOURNAL OF MEDICAL SCIENCE | 2024年 / 16卷 / 02期
关键词：
ttr cardiac amyloidosis; cardiac amyloidosis with reduced ejection fraction; diastolic heart failure; cardiac amyloidosis; immunoglobulin light-chain amyloidosis; DIAGNOSIS;
D O I：
10.7759/cureus.55271
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Systemic amyloidosis is caused by the extracellular deposition of misfolded proteins in various organs and usually leads to organ dysfunction. The two common subtypes include light -chain amyloidosis and transthyretin amyloidosis. Deposition of these proteins in the heart can lead to infiltrative and restrictive cardiomyopathy, commonly manifesting as heart failure with preserved ejection fraction. However, systolic heart failure with reduced ejection fraction is mainly seen in the advanced stages of the disease. Here, we present the case of a 53 -year -old female who presented with new -onset heart failure with reduced ejection fraction with no prior symptoms or diagnosis of amyloidosis and diastolic dysfunction.
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页数：10
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