A case of primary breast angiosarcoma diagnosed by multimodal ultrasound imaging with literature review

Primary Breast Angiosarcoma (PBA) is an exceptionally rare form of breast cancer, accounting for less than 0.05% of all breast cancers. It is characterized by a high level of malignancy, invasiveness, and has a prognosis that is typically poor. The lack of distinctive clinical features makes it prone to underdiagnosis and misdiagnosis. This study retrospectively examines a case utilizing multimodal ultrasound imaging techniques (including 2D ultrasound, contrast-enhanced ultrasound, and ultrasound elastography) for diagnosing PBA. Furthermore, the study reviews relevant literature to summarize the ultrasound characteristics of PBA, with the aim of improving understanding of this elusive condition. Primary breast angiosarcoma is an extremely rare form of breast cancer that is difficult to diagnose through 2D ultrasound alone. In this case, the diagnosis and differentiation of primary breast angiosarcoma were achieved through a combination of 2D ultrasound, contrast-enhanced ultrasound, and ultrasound elastography, highlighting the potential of multimodal ultrasound imaging to enhance the diagnostic accuracy of primary breast angiosarcoma. image