Research progress on hydroxyapatite/graphene oxide composite scaffolds in the treatment of bone defect repair

被引：0
|
作者：
Yang N. [1 ]
He X. [1 ]
机构：
[1] Department of Materials and Chemistry, University of Shanghai for Science and Technology, Shanghai
来源：
Fuhe Cailiao Xuebao/Acta Materiae Compositae Sinica | 2024年 / 41卷 / 01期
基金：
中国国家自然科学基金;
关键词：
bone diseases; composite brackets; graphene oxide; hydroxyapatite; tissue engineering;
D O I：
10.13801/j.cnki.fhclxb.20230423.001
中图分类号：
学科分类号：
摘要：
Bone defects caused by bone diseases are a very challenging issue in modern medicine. Both pathological changes in normal bone tissue and physical damage caused by external factors can lead to difficult-to-heal bone defects. The complex microenvironment of the bone defect site makes treatment conditions more demanding. Constructing scaffolds for bone defects is an important direction in bone tissue engineering technology and a crucial means to solve the problem of bone defect diseases. This article briefly introduces the preparation principles and methods of hydroxyapatite/graphene oxide (HA/GO) composite materials. HA/GO has no apparent toxicity to bone cells, and its rough surface structure is more conducive to the proliferation and differentiation of bone cells. Based on this, the construction methods and performance of HA/GO composite scaffolds for treating bone defect diseases are described in detail. Finally, the development prospects and challenges of HA/GO composite scaffolds in the treatment of bone diseases are discussed. © 2024 Beijing University of Aeronautics and Astronautics (BUAA). All rights reserved.
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页码：38 / 49
页数：11
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