Anticancer effects of exercise:Insights from single-cell analysis

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作者
Abel PlazaFlorido [1 ]
Alejandro Lucia [2 ,3 ]
Shlomit RadomAizik [1 ]
Carmen FiuzaLuces [3 ]
机构
[1] Pediatric Exercise and Genomics Research Center,Department of Pediatrics,School of Medicine,University of California Irvine
[2] Faculty of Sport Sciences,Universidad Europea de Madrid
[3] Physical Activity and Health Research Group("PaHerg"),Research Institute of the Hospital de Octubre
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G804.2 [运动生理学]; R730.1 [肿瘤的预防与控制];
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摘要
<正>A recent special topic in the Journal of Sport and Health Science reported the health benefits conferred by traditional and innovative m-health exercise and multimodal programs with respect to several types of cancer.1 A possible mechanism behind this protective effect could be enhanced cancer immunosurveillance.2,3 A single bout of exercise,such as 20—60 min of running or cycling,has been demonstrated to elicit a robust mobilization of immune effectors with a high cytotoxic capacity—notably,natural killer (NK) and CD8+T cells—into the bloodstream,with the repetition over time of these bouts ("regular"exercise) eventually resulting in higher immune infiltrates into tumors and a delayed cancer growth.3
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页码:676 / 678
页数:3
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