Evaluation on Quality of Life and Analysis on Its Correlation with TCM Syndromes in Patients of Chronic Hepatitis B

<正>Objective:To evaluate the quality of life(QOL) in patients with chronic hepatitis B(CHB) and analyze its correlation with traditional Chinese medicine(TCM) syndrome types.Methods:With cross-sectional investigation adopted,the QOL of 335 CHB patients was studied by the World Health Organization Quality of Life BREF Questionnaire(WHOQOL-BREF) and the chronic liver disease questionnaire(CLDQ).The results was compared with that of 30 healthy persons.Results:The QOL of the patients with chronic hepatitis B was lower than the healthy persons with significant difference between them(P<0.01).Also it was different in patients of different TCM syndrome types(P<0.05 or P<0.01).The lowest QOL was shown in patients of the blood-stasis blocking vessel type and Gan(肝)-stagnation with Pi(脾)-deficiency type(P<0.01).Conclusion:The QOL of CHB patients is lower than of healthy persons and closely correlated with TCM syndrome types.