MANNICH REACTIONS OF INDOLES WITH DICHLOROMETHANE AND SECONDARY-AMINES UNDER HIGH-PRESSURE

被引：17
|
作者：
MATSUMOTO, K
UCHIDA, T
HASHIMOTO, S
YONEZAWA, Y
IIDA, H
KAKEHI, A
OTANI, S
机构：
[1] FUKUI UNIV,FAC EDUC,FUKUI 910,JAPAN
[2] KYOTO UNIV,FAC INTEGRATED HUMAN STUDIES,KYOTO 606,JAPAN
[3] SHINSHU UNIV,FAC ENGN,NAGANO 380,JAPAN
来源：
HETEROCYCLES | 1993年 / 36卷 / 10期
关键词：
D O I：
10.3987/COM-93-6451
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Mannich reactions of indole with dichloromethane and secondary amines gave the corresponding Mannich bases in moderate to good yields, while 2-methylindole afforded only low yields of the Mannich bases. Some limitations were observed in the cases of hindered amines and 2-phenylindole.
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页码：2215 / 2219
页数：5
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