THE GENETICS OF MULTIPLE ENDOCRINE NEOPLASIA SYNDROMES

被引：3
|
作者：
NANES, MS
CATHERWOOD, BD
机构：
[1] VET AFFAIRS MED CTR,ATLANTA,GA 30033
[2] EMORY UNIV,SCH MED,DEPT ANAT CELL BIOL,ATLANTA,GA 30033
来源：
ANNUAL REVIEW OF MEDICINE | 1992年 / 43卷
关键词：
HYPERPARATHYROIDISM; PHEOCHROMOCYTOMA; ZOLLINGER-ELLISON SYNDROME; INSULINOMA; MEDULLARY THYROID CARCINOMA; NEOPLASIA;
D O I：
10.1146/annurev.med.43.1.253
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
The familial nature of multiple endocrine neoplasia syndromes (FMEN) has been recognized for some time but little is known about their cause. Recent application of new molecular techniques has mapped FMEN syndromes to specific chromosomes and provided evidence for the mechanism through which neoplasia occurs. In this review, we describe the techniques that led to recent advances in our understanding of FMEN and we discuss the evidence supporting proposed molecular mechanisms of neoplasia.
引用
收藏
页码：253 / 268
页数：16
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