IFOSFAMIDE-INDUCED NONCONVULSIVE STATUS EPILEPTICUS

被引:31
|
作者
WENGS, WJ [1 ]
TALWAR, D [1 ]
BERNARD, J [1 ]
机构
[1] UNIV MINNESOTA,SCH MED,CTR HLTH,DEPT NEUROL,BOX 295,MINNEAPOLIS,MN 55455
关键词
D O I
10.1001/archneur.1993.00540100089024
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
We report the first case of nonconvulsive status epilepticus as a complication of chemotherapy with the nitrogen mustard derivative ifosfamide. Our patient developed encephalopathy, upper extremity myoclonus, and a periodic, triphasic electroencephalogic pattern that resolved acutely with intravenous diazepam treatment. Since significant morbidity and mortality is associated with unrecognized status epilepticus, electroencephalogic monitoring and a trial of diazepam is indicated in encephalopathic patients with rhythmic electroencephalogic patterns while receiving treatment with ifosfamide.
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收藏
页码:1104 / 1105
页数:2
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