INFECTIOUS ENTRY PATHWAY OF ADENOVIRUS TYPE-2

被引：101
|
作者：
VARGA, MJ
WEIBULL, C
EVERITT, E
机构：
来源：
JOURNAL OF VIROLOGY | 1991年 / 65卷 / 11期
关键词：
D O I：
10.1128/JVI.65.11.6061-6070.1991
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Internalization of the infectious fraction of human adenovirus type 2 into HeLa cells was followed by a quantitative internalization assay. Treatments known to selectively block receptor-mediated endocytosis reduced the internalization of infectious virus to an extent close to the reduction of endocytosis of transferrin. This suggests that one of the first steps in the infectious cycle of adenovirus type 2 is internalization by the coated-pit and -vesicle pathway.
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页码：6061 / 6070
页数：10
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