CELLULAR AND MUSCLE ZINC IN SURGICAL PATIENTS WITH AND WITHOUT GASTROINTESTINAL CANCER

被引:6
|
作者
GOODE, HF [1 ]
KELLEHER, J [1 ]
WALKER, BE [1 ]
HALL, RI [1 ]
GUILLOU, PJ [1 ]
机构
[1] UNIV LEEDS,ST JAMES HOSP,DEPT SURG,LEEDS LS9 7TF,W YORKSHIRE,ENGLAND
关键词
alkaline phosphatase; gastrointestinal neoplasms; leucocytes; muscles; zinc;
D O I
10.1042/cs0790247
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
1. The zinc status of surgical patients with and without gastrointestinal cancer was studied. 2. Plasma zinc was lowest in patients with cancer concurrent with depressed plasma albumin concentrations. 3. Polymorphonuclear cell zinc was decreased in both patient groups and correlated strongly with abdominal muscle zinc (r = 0.89, P < 0.001). 4. Mononuclear cell and total leucocyte zinc were similar to control values in both groups of patients. Total leucocyte, but not mononuclear cell, zinc correlated weakly with muscle zinc (r = 0.48, P < 0.05). 5. The results suggest that polymorphonuclear cell zinc may be better than leucocyte zinc in assessing zinc status and that some surgical patients may be zinc-depleted. The presence of gastrointestinal cancer did not influence the zinc status.
引用
收藏
页码:247 / 252
页数:6
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