FLUORESCENT MULTIPLEX MICROSATELLITES USED TO IDENTIFY HAPLOTYPE ASSOCIATIONS WITH 15 CFTR MUTATIONS IN 124 NORTHERN IRISH CF FAMILIES

被引：0

作者：

HUGHES, D

HILL, A

REDMOND, A

NEVIN, N

GRAHAM, C

机构：

[1] QUEENS UNIV BELFAST,DEPT MED GENET,BELFAST,ANTRIM,NORTH IRELAND

[2] BELFAST CITY HOSP TRUST,CTR REG GENET,BELFAST,ANTRIM,NORTH IRELAND

[3] ROYAL BELFAST HOSP SICK CHILDREN,BELFAST,ANTRIM,NORTH IRELAND

来源：

HUMAN GENETICS | 1995年 / 95卷 / 04期

关键词：

D O I：

暂无

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The cystic fibrosis transmembrane conductance regulator gene contains three highly informative microsatellites; IVS8CA, IVS17BTA and IVS17BCA. Fluorescent multiplexes of these microsatellites were assayed in 124 CF families carrying 15 different CFTR mutations, from N. Ireland.

引用

页码：462 / 464

页数：3

共 2 条

[1] Fluorescent multiplex microsatellites used to define haplotypes associated with 75 CFTR mutations from the UK on 437 CF chromosomes
Hughes, D
Wallace, A
Taylor, J
Tassabehji, M
McMahon, R
Hill, A
Nevin, N
Graham, C
HUMAN MUTATION, 1996, 8 (03) : 229 - 235
[2] Mutation characterization of CFTR gene in 206 Northern Irish CF families: Thirty mutations, including two novel, account for similar to 94% of CF chromosomes
Hughes, DJ
Hill, AJM
Macek, M
Redmond, AO
Nevin, NC
Graham, CA
HUMAN MUTATION, 1996, 8 (04) : 340 - 347

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