PIGMENT GRANULE MIGRATION AND PHOTOTRANSDUCTION ARE TRIGGERED BY SEPARATE PATHWAYS IN FLY PHOTORECEPTOR CELLS

被引：5
|
作者：
HANYU, Y [1 ]
FRANCESCHINI, N [1 ]
机构：
[1] ELECTROTECH LAB, BIOPHYS SECT, TSUKUBA 305, JAPAN
来源：
NEUROREPORT | 1993年 / 4卷 / 02期
关键词：
FLY PHOTORECEPTORS; PIGMENT GRANULE MIGRATION; PHOTOADAPTATION; METARHODOPSIN; PHOTOCONVERSION; CYCLIC GMP; CALCIUM IONS; SODIUM NITROPRUSSIDE; GUANYLATE CYCLASE;
D O I：
10.1097/00001756-199302000-00026
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
WE studied the mechanism of pigment granule migration in fly photoreceptors. We found that these granules migrate transiently with red light stimulation. This suggests that excitation of metarhodopsin triggers granule migration. We also found that cyclic GMP is one of the activators of pigment granule migration. These findings suggest that pigment granule migration is triggered separately from phototransduction, which is initiated by the excitation of rhodopsin.
引用
收藏
页码：215 / 218
页数：4
相关论文
共 11 条
  • [1] PATHWAYS OF VISUAL PIGMENT REGENERATION IN FLY PHOTORECEPTOR CELLS
    SCHWEMER, J
    [J]. BIOPHYSICS OF STRUCTURE AND MECHANISM, 1983, 9 (04): : 287 - 298
  • [2] CALCIUM ENABLES PHOTORECEPTOR PIGMENT MIGRATION IN A MUTANT FLY
    HOWARD, J
    [J]. JOURNAL OF EXPERIMENTAL BIOLOGY, 1984, 113 (NOV): : 471 - 475
  • [3] PIGMENT GRANULE MIGRATION IN ISOLATED CELLS OF THE TELEOST RETINAL-PIGMENT EPITHELIUM
    BRUENNER, U
    BURNSIDE, B
    [J]. JOURNAL OF CELL BIOLOGY, 1984, 99 (04): : A51 - A51
  • [4] PIGMENT GRANULE MIGRATION IN ISOLATED CELLS OF THE TELEOST RETINAL-PIGMENT EPITHELIUM
    BRUENNER, U
    BURNSIDE, B
    [J]. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 1986, 27 (11) : 1634 - 1643
  • [5] ROLE OF MICROTUBULES IN PIGMENT GRANULE MIGRATION IN TELEOST RETINAL-PIGMENT EPITHELIAL-CELLS
    TROUTT, LL
    BURNSIDE, B
    [J]. EXPERIMENTAL EYE RESEARCH, 1989, 48 (03) : 433 - 443
  • [6] Bidirectional pigment granule migration in isolated retinal pigment epithelial cells requires actin but not microtubules
    KingSmith, C
    Paz, P
    Lee, CW
    Lam, W
    Burnside, B
    [J]. CELL MOTILITY AND THE CYTOSKELETON, 1997, 38 (03): : 229 - 249
  • [7] CYTOSKELETON OF RETINULAR CELLS FROM THE STOMATOPOD, GONODACTYLUS-OERSTEDII - POSSIBLE ROLES IN PIGMENT GRANULE MIGRATION
    KING, CA
    CRONIN, TW
    [J]. CELL AND TISSUE RESEARCH, 1993, 274 (02) : 315 - 328
  • [8] Adrenomedullin affects two signal transduction pathways and the migration in retinal pigment epithelial cells
    Huang, W
    Wang, L
    Yuan, M
    Ma, JX
    Hui, YN
    [J]. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2004, 45 (05) : 1507 - 1513
  • [9] Lutein Inhibits the Migration of Retinal Pigment Epithelial Cells via Cytosolic and Mitochondrial Akt Pathways (Lutein Inhibits RPE Cells Migration)
    Su, Ching-Chieh
    Chan, Chi-Ming
    Chen, Han-Min
    Wu, Chia-Chun
    Hsiao, Chien-Yu
    Lee, Pei-Lan
    Lin, Victor Chia-Hsiang
    Hung, Chi-Feng
    [J]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2014, 15 (08) : 13755 - 13767
  • [10] LIGHT-INDUCED PIGMENT GRANULE MIGRATION IN THE RETINULAR CELLS OF DROSOPHILA-MELANOGASTER - COMPARISON OF WILD-TYPE WITH ERG-DEFECTIVE MUTANTS
    LO, MVC
    PAK, WL
    [J]. JOURNAL OF GENERAL PHYSIOLOGY, 1981, 77 (02): : 155 - 175
12