Risk factors for cardiovascular disease have been shown to cluster in adult populations of men and women [Criqui et al., 1980]. In a population of adult female twin pairs (ages 18-85), body mass index, systolic and diastolic blood pressure, and high and low density lipoprotein levels were found to exhibit significant clustering. Path analysis was used to resolve the risk factor correlations into genetic, environmental, and age-related components. (C) 1993 Wiley-Liss, Inc.
机构:
NORTHWICK PK HOSP,MRC,EPIDEMIOL & MED CARE UNIT,HARROW HA1 3UJ,MIDDLESEX,ENGLANDNORTHWICK PK HOSP,MRC,EPIDEMIOL & MED CARE UNIT,HARROW HA1 3UJ,MIDDLESEX,ENGLAND