Polycystic Liver Disease with Huge Infected Cyst Displacing the Pancreas, Inferior Vena Cava and Right Kidney

Multiple liver cysts can be an isolated disease (isolated polycystic liver disease [PLD]) or they can be part of multi-organ involvement in other diseases, such as adult autosomal dominant polycystic disease (APD), which is the most frequently inherited polycystic disease affecting 1 in 1,000 of the population. About 33% of APD patients are expected to develop PLD. Cysts in the liver, as opposed to cysts in the kidney, grow dramatically in number and size. They are usually asymptomatic but may present with signs and symptoms of compression of adjacent organs as the cysts grow. We present a case of a 73 year-old female patient with PLD and a large (25 x 19 x 18 cm) infected cyst which caused the displacement of the inferior vena cava, right kidney, and pancreas. We also discuss the management of this patient along with a review of the literature.