The present article is a summary of current knowledge on mechanisms of viral etiopathogenesis in non-Hodgkin lymphomas (NHL). Some data has proved an oncogenic significance of Epstein-Barr (EBV) and human T-cell leukemia/lymphoma virus type I (HTLV-I). In case of others, including human immunodeficiency virus (HIV-1 and HIV-2), hepatitis type C (HCV), cytomegalovirus (CMV), human herpesvirus type 8 (HHV-8), SV-40 or HTLV-II, there are some evidences suggesting their participation in the development of NHL, however their real role in this phenomenon has not been proved so far. Scientific insights into ethiopathogenesis of NHL provide not only theoretical value but also important diagnostic and therapeutic implications in this group of malignancies.
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Ctr Antoine Lacassagne, Dept Med Oncol, 33 Ave Valombrose, F-06000 Nice, FranceCtr Antoine Lacassagne, Dept Med Oncol, 33 Ave Valombrose, F-06000 Nice, France
Gastaud, L.
Rossignol, B.
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Ctr Hosp Dracenie, Dept Oncol & Hematol, Route Montferrat, F-83300 Draguignan, FranceCtr Antoine Lacassagne, Dept Med Oncol, 33 Ave Valombrose, F-06000 Nice, France
Rossignol, B.
Peyrade, F.
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Ctr Antoine Lacassagne, Dept Med Oncol, 33 Ave Valombrose, F-06000 Nice, FranceCtr Antoine Lacassagne, Dept Med Oncol, 33 Ave Valombrose, F-06000 Nice, France
Peyrade, F.
Re, D.
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Ctr Hosp Antibes Juan Les Pins, Dept Med Interne Gastroenterol Cancerol & Rhumato, 107 Ave Nice, F-06606 Antibes, FranceCtr Antoine Lacassagne, Dept Med Oncol, 33 Ave Valombrose, F-06000 Nice, France
Re, D.
Thariat, J.
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Ctr Antoine Lacassagne, Dept Radiotherapie, 33 Ave Valombrose, F-06000 Nice, FranceCtr Antoine Lacassagne, Dept Med Oncol, 33 Ave Valombrose, F-06000 Nice, France
Thariat, J.
Thyss, A.
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Ctr Antoine Lacassagne, Dept Med Oncol, 33 Ave Valombrose, F-06000 Nice, FranceCtr Antoine Lacassagne, Dept Med Oncol, 33 Ave Valombrose, F-06000 Nice, France
Thyss, A.
Doyen, J.
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Ctr Antoine Lacassagne, Dept Radiotherapie, 33 Ave Valombrose, F-06000 Nice, FranceCtr Antoine Lacassagne, Dept Med Oncol, 33 Ave Valombrose, F-06000 Nice, France
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Mem Sloan Kettering Canc Ctr, Dept Radiat Oncol, 1275 York Ave, New York, NY 10021 USAMem Sloan Kettering Canc Ctr, Dept Radiat Oncol, 1275 York Ave, New York, NY 10021 USA
Imber, Brandon S.
Yahalom, Joachim
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Mem Sloan Kettering Canc Ctr, Lymphoma Dis Management Team, Koch Bldg,530 E 74th St, New York, NY 10021 USAMem Sloan Kettering Canc Ctr, Dept Radiat Oncol, 1275 York Ave, New York, NY 10021 USA