SYNTHESIS OF 5-HYDROXY-3-TRIFLUOROMETHYL-PYRAZOLES BY RING-OPENING OF 3-TRIFLUOROACETYL-BENZOLACTAMS

被引：0
|
作者：
BOUILLON, JP [1 ]
JANOUSEK, Z [1 ]
VIEHE, HG [1 ]
TINANT, B [1 ]
DECLERCQ, JP [1 ]
机构：
[1] UNIV CATHOLIQUE LOUVAIN,CHIM PHYS P CRISTALLOG LAB,B-1348 LOUVAIN,BELGIUM
来源：
BULLETIN DES SOCIETES CHIMIQUES BELGES | 1994年 / 103卷 / 11期
关键词：
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
New trifluoromethylated pyrazoles 5b,c,f have been prepared by condensation of 3-trifluoroacetyl benzolactams 1a,b,c and 2 with hydrazines by opening of the lactam moiety. The structure of pyrazoles was established by X-ray diffraction analysis and by comparison of C-13-NMR data. The geometry of intermediate hydrazones 3c-e and their cyclisations were also investigated.
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页码：655 / 664
页数：10
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