Traumatic Optic Neuropathy: A Review

被引:57
|
作者
Kumaran, Arjunan Muthu [1 ]
Sundar, Gangadhara [2 ]
Lim, Thiam Chye [3 ]
机构
[1] Natl Univ Singapore, Yong Loo Lin Sch Med, Singapore 117595, Singapore
[2] Natl Univ Hlth Syst, Natl Univ Hosp, Dept Ophthalmol, 1E Kent Ridge Rd,NUHS Tower,Block Level 7, Singapore 119228, Singapore
[3] Natl Univ Hlth Syst, Natl Univ Hosp, Div Plast Reconstruct & Aesthet Surg, Singapore 119228, Singapore
关键词
traumatic optic neuropathy; oculofacial trauma; corticosteroid therapy; optic nerve decompression; neuroprotection and neuroregeneration;
D O I
10.1055/s-0034-1393734
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
The aim of this article is to evaluate current literature on investigation and management of traumatic optic neuropathy (TON), propose recommendations for diagnosis and management, and explore novel future treatments. TON, though uncommon, causes substantial visual loss. Without clear guidelines, there is much ambiguity regarding its diagnosis and management. Investigation and treatment (conservative, medical, surgical, and combined) vary widely between centers. Electronic databases PubMed, MEDLINE, PROSPERO, CENTRAL, and EMBASE were searched for content that matched "Traumatic optic neuropathy." Articles with abstracts and full text available, published in the past 10 years, written English and limited to human adults, were selected. All study designs were acceptable except case reports and case series with fewer 10 patients. All abstracts were then evaluated for relevance. References of these studies were evaluated and if also relevant, included. A total of 2,686 articles were retrieved and 43 examined for relevance. Of these, 23 articles were included. TON is a clinical diagnosis. Visuale-voked potential is useful in diagnosis and prognosis. Computed tomography demonstrates canal fractures and concomitant injuries. Magnetic resonance images should be reserved for select and stable patients. Conservative treatment is appropriate in mild TON. Steroids are of questionable benefit and may be harmful. Surgery should be reserved for patients with radiological evidence of compression and individualized.
引用
收藏
页码:31 / 41
页数:11
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