There is a link between obesity and both, asthma and COPD. Aim of the work: To study effect of weight reduction on pulmonary function tests of obese COPD and bronchial asthma patients. Subjects and methods: 2 groups were included, group(G) I, 30 obese COPD and GII 30 obese bronchial asthma patients. Pulmonary function tests were done to all participants before and after weight reduction. Results: GI showed increased FRC, ERV and RV significantly, IC was significantly decreased and GII showed increased FEV1, FVC, FEV1/FVC, PEFR, FEF25-75% and ERV significantly after weight reduction. Conclusion: Weight reduction improved airway obstruction, increased ERV, RV, FRC and DLCO either significant or insignificant in asthma and COPD. (C) 2015 The Authors. Production and hosting by Elsevier B.V. on behalf of The Egyptian Society of Chest Diseases and Tuberculosis.