ORAL NEUROFIBROSARCOMA ASSOCIATED WITH NEUROFIBROMATOSIS TYPE-I

被引:22
|
作者
NEVILLE, BW
HANN, J
NARANG, R
GAREN, P
机构
[1] MED UNIV S CAROLINA, COLL DENT MED, DEPT ORAL & MAXILLOFACIAL SURG, CHARLESTON, SC 29425 USA
[2] MED UNIV S CAROLINA, COLL MED, DEPT PATHOL, CHARLESTON, SC 29425 USA
[3] MED UNIV S CAROLINA, COLL MED, DEPT LAB MED, CHARLESTON, SC 29425 USA
关键词
D O I
10.1016/0030-4220(91)90560-Y
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
One of the most feared complications of neurofibromatosis type I (NF-I) is development of cancer, which is estimated to occur in about 5% of cases. The most common associated malignancy is the neurofibrosarcoma (NFS). However, oral NFS in association with NF-I has rarely been reported. We report two cases of oral NFS arising in patients with NF-I. Both patients died of their tumors. Oral NFS arising in association with NF-I appears to have an extremely poor prognosis, as do these tumors at other sites of the body.
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页码:456 / 461
页数:6
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