THEOPHYLLINE REVERSAL OF ELECTROCONVULSIVE-THERAPY (ECT) SEIZURE INHIBITION

被引：30
|
作者：
SWARTZ, CM
LEWIS, RK
机构：
[1] VET ADM MED CTR,N CHICAGO,IL 60064
[2] UNIV HLTH SCI CHICAGO MED SCH,DEPT PHARMACOL,N CHICAGO,IL 60064
来源：
PSYCHOSOMATICS | 1991年 / 32卷 / 01期
关键词：
D O I：
10.1016/S0033-3182(91)72110-5
中图分类号：
R749 [精神病学];
学科分类号：
100205 ;
摘要：
Oral sustained-release theophylline 200-400 mg, given 10 hours prior to electroconvulsive therapy (ECT) increased ECT seizure length in each of eight male patients who had shown unacceptably short seizures. The increase was on average 13.9 (+/- 6.0, SD) sec (p = .00016 by t test; p = .0000034 by exact probability). The absence of unduly prolonged seizures was attributed to previously demonstrated high seizure thresholds and to relatively low concentrations of theophylline. No adverse effects from theophylline were seen.
引用
收藏
页码：47 / 51
页数：5
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