Staphylococcal infections;
Vancomycin resistance;
Methicillin;
Endocarditis;
Bacterial;
Health personnel;
D O I:
暂无
中图分类号:
R-3 [医学研究方法];
R3 [基础医学];
学科分类号:
1001 ;
摘要:
Methicillin-resistant Staphylococcus aureus (MRSA) which emerged in hospitals in 1961 is now a leading cause of associated healthcare infections. The MRSA which is a Staphylococcus infection remarkably developed resistance to methicillin which was used to treat it. This review covers the epidemiology, pathophysiology, clinical manifestations, diagnostic measures, and effective management of MRSA. Currently, MRSA infection is encountered in small community hospitals, which leads to community-acquired MRSA (CA-MRSA) when the patients are discharged and introduce the strain into the community. MRSA can lead to diverse infection such as skin and soft tissue infections, bone and joint infections, and acute bacterial endocarditis. MRSA incidence is increasing in the population, and therapeutic measures are few and accompanied by diverse side effects notably the ability to develop resistance by S. aureus. Therefore, a well-formulated strategy which will prevent the spread of the pathogen is always a priority for healthcare providers. It is noteworthy to state that Vancomycin is still the first line drug although a Vancomycin-resistant strain has been reported.
机构:
Ilam Univ Med Sci, Clin Microbiol Res Ctr, Ilam 6931619, IranIlam Univ Med Sci, Clin Microbiol Res Ctr, Ilam 6931619, Iran
Nazari, Mohammad Reza
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Sekawi, Zamberi
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Sadeghifard, Nourkhoda
Raftari, Mohammad
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Univ Putra Malaysia, Fac Med & Hlth Sci, Dept Med Microbiol & Parasitol, Serdang, MalaysiaIlam Univ Med Sci, Clin Microbiol Res Ctr, Ilam 6931619, Iran
Raftari, Mohammad
Ghafourian, Sobhan
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机构:
Ilam Univ Med Sci, Clin Microbiol Res Ctr, Ilam 6931619, IranIlam Univ Med Sci, Clin Microbiol Res Ctr, Ilam 6931619, Iran
机构:
Royal Prince Alfred Hosp, Dept Infect Dis, Sydney, NSW, Australia
Royal Prince Alfred Hosp, Dept Microbiol, Sydney, NSW, Australia
Univ Sydney, Fac Med, Sydney, NSW, AustraliaRoyal Prince Alfred Hosp, Dept Infect Dis, Sydney, NSW, Australia
Lee, Andie S.
de Lencastre, Herminia
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机构:
Rockefeller Univ, Lab Microbiol & Infect Dis, 1230 York Ave, New York, NY 10021 USA
Univ Nova Lisboa, Inst Tecnol Quim & Biol Antonio Xavier, Lab Mol Genet, Oeiras, PortugalRoyal Prince Alfred Hosp, Dept Infect Dis, Sydney, NSW, Australia
de Lencastre, Herminia
Garau, Javier
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Hosp Univ Mutua Terrassa, Dept Med, Barcelona, SpainRoyal Prince Alfred Hosp, Dept Infect Dis, Sydney, NSW, Australia
Garau, Javier
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Kluytmans, Jan
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Malhotra-Kumar, Surbhi
Peschel, Andreas
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Univ Tubingen, Interfac Inst Microbiol & Infect Med, Dept Infect Biol, Tubingen, Germany
German Ctr Infect Res, Partner Site Tubingen, Tubingen, GermanyRoyal Prince Alfred Hosp, Dept Infect Dis, Sydney, NSW, Australia
Peschel, Andreas
Harbarth, Stephan
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机构:
Univ Geneva Hosp, Infect Control Programme, Geneva, Switzerland
WHO Collaborating Ctr, Fac Med, Geneva, SwitzerlandRoyal Prince Alfred Hosp, Dept Infect Dis, Sydney, NSW, Australia
机构:
S Western Area Pathol Serv, Dept Microbiol & Infect Dis, Liverpool, NSW, AustraliaS Western Area Pathol Serv, Dept Microbiol & Infect Dis, Liverpool, NSW, Australia