CLINICAL UTILITY OF UNBOUND ANTIEPILEPTIC DRUG BLOOD-LEVELS IN THE MANAGEMENT OF EPILEPSY

被引:42
|
作者
LENN, NJ [1 ]
ROBERTSON, M [1 ]
机构
[1] UNIV VIRGINIA,MED CTR,SCH MED,DEPT NEUROL,CHARLOTTESVILLE,VA 22901
关键词
D O I
10.1212/WNL.42.5.988
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
We tabulated all unbound and total antiepileptic blood levels collected in 13 months. According to strict criteria, 24% of phenytoin and 15% of valproate unbound blood levels but none of the carbamazepine unbound levels had clinical significance in the management of seizures or side effects. These data support frequent use of unbound phenytoin or valproate blood levels in the management of epilepsy.
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页码:988 / 990
页数:3
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