Studies of Phenolic Constituents and Biological Activities of Livistona decipiens Leaves (Fam. Arecaceae)

This study focused on isolation and identification of secondary metabolites from the alcoholic extract of Livstona decipiens leaves for the first time, as well as evaluation of its biological activities. The n-butanol extract was subjected to polyamide 6 column chromatography and ten flavonoids were isolated, the isolated compounds were identified as; Schaftoside (1), Isoorientin (2), Tricin-7-O-glucoside (3), Quercetin (4), Luteolin (5), Orientin (6), Luteolin-7-O-glucoside (7), Quercetin-3-O-galactoside (8), Apigenin (9) and Tricin (10), and their structures were established on the basis of different spectroscopic techniques. Antioxidant, analgesic, anti-inflammatory and antihyperglycemic activities of the extracts were evaluated. Determination of the median lethal dose (LD50) revealed that the extracts of the plant are safe and no lethality was observed up to 24 hours after treatment. The ethanolic extract was found to exhibit remarkable analgesic, antihyperglycemic and anti-inflammatory, while n-butanol extract showed significant antioxidant activity, so this plant is a new source for phenolic compounds and due to its low toxicity, it is an effective medicinal agent for the use in the treatment of human diseases.