HISTOPATHOLOGICAL DIAGNOSIS CRITERIA IN ENDOMETRIAL HYPERPLASIA

Endometrial hyperplasia is a condition of the abnormal proliferative lesions of the endometrium. Aim: To highlight the value of histopathological examinations with assessment of the ways to obtain endometrial biopsies and the appreciation of the contribution of different histopathological techniques that can be used to establish a correct and complete diagnosis. Material and methods: The study was conducted in a group of 50 patients diagnosed with endometrial hyperplasia. In all cases the bioptic curettage was performed using a curette to obtain more abundant material for the histopathological examination. Results: Histopathological diagnosis guides the therapeutic attitude and has an important prognostic value. The study group was characterized by histoarchitectonic heterogeneity, presented even in the same case. Histoarchitectonic and cytological changes differentiate endometrial hyperplasia from physiological proliferative endometrium. Conclusions: The diagnosis of certainty between the four types of endometrial proliferation established by the WHO can only be done through the histopathological examination.