IN-111 LABELED MN-METALLOPORPHYRIN FOR TUMOR IMAGING

被引：17
|
作者：
NAKAJIMA, S
YAMAUCHI, H
SAKATA, I
HAYASHI, H
YAMAZAKI, K
MAEDA, T
KUBO, Y
SAMEJIMA, N
TAKEMURA, T
机构：
[1] NIHONMEDIPHYS CO LTD,CHIBA 29902,JAPAN
[2] TOYOHAKKA CO LTD,OKAYAMA 71003,JAPAN
[3] HOKKAIDO UNIV,INST APPL ELECT,DEPT CHEM,SAPPORO,HOKKAIDO 060,JAPAN
[4] ASAHIKAWA MED COLL,DEPT SURG 1,ASAHIKAWA 078,JAPAN
来源：
NUCLEAR MEDICINE AND BIOLOGY | 1993年 / 20卷 / 02期
关键词：
D O I：
10.1016/0969-8051(93)90120-J
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
We synthesized and developed a new tumor imaging agent, In-111-labeled metalloporphyrin (In-111-ATN-10) which consists of a carrier (ATN-10) of the tumor imaging possessing both a non-radioactive manganese complex in the porphyrin ring and a bifunctional chelating group (DTPA) attached to its side chain. The images of the three kinds of tumors were delineated more clearly by In-111-ATN-10 than Ga-67-citrate. Moreover, there was no photosensitivity in ATN-10. In-111-ATN-10 is studied as a new tumor positive scintigraphic agent instead of Ga-67-citrate.
引用
收藏
页码：231 / 237
页数：7
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