ALPHA-KETOGLUTARATE AND POSTOPERATIVE MUSCLE CATABOLISM

被引：98
|
作者：
WERNERMAN, J
HAMMARQVIST, F
VINNARS, E
机构：
[1] KAROLINSKA INST,ST GORANS CHILDRENS HOSP,DEPT SURG,S-11281 STOCKHOLM,SWEDEN
[2] KAROLINSKA INST,ST GORANS CHILDRENS HOSP,METAB RES LAB,S-11281 STOCKHOLM,SWEDEN
来源：
LANCET | 1990年 / 335卷 / 8691期
关键词：
D O I：
10.1016/0140-6736(90)90811-I
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The hypothesis that muscle protein catabolism after trauma is associated with a shortage of α-ketoglutarate, rather than glutamine, was tested. Addition of α-ketoglutarate to postoperative total parenteral nutrition prevented the decrease in muscle protein synthesis and free glutamine that usually occurs after surgery. α-ketoglutarate supplementation may improve recovery after trauma. © 1990.
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页码：701 / 703
页数：3
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