The present paper aims to offer insight regarding the post-anthropocentric elements present in one of Samuel Beckett's most innovative plays, Krapp's Last Tape. In order to support my premise, I wrote a comprehensive theoretical outline of posthumanism, taking into account aspects such as the adaptation of the brain to new technologies and the influence they exert, the appearance and usage of prosthetics, symbiotic relationships and the interconnectedness between body, mind and environment. I then proceeded to offer my own interpretation of the target text, focusing on Beckett's recurrent tendency to represent the body as an aged, decaying and fallible organic vessel and relevant human-machine symbiosis. Humanity's centrality is deconstructed by focalising on its subservience to suffering.