CANCER CYTOGENETICS AND MOLECULAR-GENETICS - CLINICAL IMPLICATIONS (REVIEW)

被引：0
|
作者：
SANDBERG, AA
CHEN, Z
机构：
来源：
INTERNATIONAL JOURNAL OF ONCOLOGY | 1995年 / 7卷 / 06期
关键词：
CANCER CYTOGENETICS; MOLECULAR GENETICS; ONCOGENES; TUMOR-SUPPRESSOR GENES;
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Cancer genetics has become a burgeoning area of both cytogenetic and molecular genetic research and practical clinical application of the findings of such research in human cancer and leukemia. This review summarizes the specific types of chromosomal and associated molecular genetic alterations in leukemia and cancer. The primary objective is to acquaint physicians of various disciplines with the application of cytogenetics and molecular genetics as diagnostic, prognostic and therapeutic indices, as approaches to the evaluation of minimal residual disease and as guides for differentiation therapy and the molecular localization of oncogenes and tumor suppressor genes related to gene therapy in leukemias and cancers.
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页码：1241 / 1251
页数：11
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