REACTION OF RUPPERT REAGENT (TMS-CF3) WITH OXAZOLIDINONES - SYNTHESIS OF PROTECTED ALPHA-AMINO TRIFLUOROMETHYLKETONES

被引：27

作者：

WALTER, MW ^{[1
]}

ADLINGTON, RM ^{[1
]}

BALDWIN, JE ^{[1
]}

CHUHAN, J ^{[1
]}

SCHOFIELD, CJ ^{[1
]}

机构：

[1] OXFORD CTR MOLEC SCI,OXFORD OX1 3QY,ENGLAND

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 42期

关键词：

D O I：

10.1016/0040-4039(95)01619-S

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

(Trifluoromethyl)trimethylsilane adds to alpha-amino acid derived oxazolidin-5-ones in excellent yields. The adducts can be converted into protected alpha-amino trifluoromethylketones by acid hydrolysis.

引用

页码：7761 / 7764

页数：4

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