ON LINE DETERMINATION OF PERPHENAZINE USING FLOW-INJECTION ANALYSIS

被引：7
|
作者：
SULTAN, SM
ABDENNABI, AM
机构：
[1] King Fahd Univ, Dept Chem, Dhahran, 31261
来源：
MICROCHEMICAL JOURNAL | 1993年 / 48卷 / 03期
关键词：
D O I：
10.1006/mchj.1993.1107
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
An accurate specific flow injection spectrophotometric method for the determination of perphenazine in the range 50-250 ppm is introduced. In the method, 110 μl of the drug is injected through a stream of 0.2% (w/v) potassium dichromate in 0.25 M sulfuric acid flowing on line as a carrier stream. The drug is oxidized on the flow to the red monocation radical, the peak absorbance of which is monitored at 525 nm. A throughput of up to 300 samples per hour is attained. The mechanism of the reaction is suggested and the method is compared with the United States Pharmacopeia method. © 1993 Academic Press. All rights reserved.
引用
收藏
页码：343 / 348
页数：6
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