THE SYNTHESIS, COOLIGOMERIZATION AND HYBRIDIZATION OF A THYMINE-THYMINE HETERODIMER CONTAINING PNA

被引：13
|
作者：
LAGRIFFOUL, PH
EGHOLM, M
NIELSEN, PE
BERG, RH
BUCHARDT, O
机构：
[1] UNIV COPENHAGEN,HC ORSTED INST,CHEM LAB 2,MED BIOTECHNOL RES CTR,DK-2100 COPENHAGEN O,DENMARK
[2] UNIV COPENHAGEN,PANUM INST,DEPT MED BIOCHEM & GENET,MED BIOCHEM LAB B,DK-2200 COPENHAGEN N,DENMARK
[3] RISO NATL LAB,DEPT MAT,POLYMER GRP,DK-4000 ROSKILDE,DENMARK
来源：
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1994年 / 4卷 / 08期
关键词：
D O I：
10.1016/S0960-894X(01)80685-5
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
A peptide nucleic acid (PNA) decamer in which one of the amide bonds between two units is reversed was prepared and its binding affinity to complementary DNA is shown to be preserved.
引用
收藏
页码：1081 / 1082
页数：2
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