The preovulatory LH surge - A case of a neuroendocrine switch

被引:37
|
作者
Clarke, IJ
机构
来源
关键词
D O I
10.1016/1043-2760(95)95218-T
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The preovulatory surge in LH is a unique endocrine event that involves a switch from the negative feedback effect of estrogen to a positive feedback effect. This occurs at both the level of the brain and that of the pituitary gland. Within the brain the mechanism appears ro involve disinhibition of negative inputs to GnRH neurons, as well as stimulation of positive inputs. The positive feedback effects on the brain and the pituitary appear to be coordinated so that the effect of estrogen involves a number of time-delayed mechanisms.
引用
收藏
页码:241 / 247
页数:7
相关论文
共 50 条
  • [1] SOME CHRONOBIOLOGICAL ASPECTS OF LH PREOVULATORY SURGE
    TESTART, J
    FRYDMAN, R
    FEINSTEIN, MC
    ROGER, M
    SCHOLLER, R
    [J]. PATHOLOGIE BIOLOGIE, 1982, 30 (07): : 653 - 654
  • [2] BLOCKADE OF PREOVULATORY LH SURGE BY METHADONE IN RATS
    JOHNSON, JH
    ROSECRANS, JA
    [J]. RESEARCH COMMUNICATIONS IN CHEMICAL PATHOLOGY AND PHARMACOLOGY, 1978, 19 (03): : 435 - 444
  • [3] A comparison of the neuroendocrine mechanisms underlying the initiation of the preovulatory LH surge in the human, Old World monkey and rodent
    Plant, Tony M.
    [J]. FRONTIERS IN NEUROENDOCRINOLOGY, 2012, 33 (02) : 160 - 168
  • [4] The role of noradrenaline in the generation of the preovulatory LH surge in the ewe
    Clarke, Iain J.
    Scott, Christopher J.
    Pereira, Alda
    Pompolo, Sueli
    [J]. DOMESTIC ANIMAL ENDOCRINOLOGY, 2006, 30 (04) : 260 - 275
  • [5] STUDIES ON THE INVOLVEMENT OF ADRENALINE IN THE RAT PREOVULATORY LH SURGE
    MACKINNON, PCB
    SHEAVES, R
    WARBURTON, E
    [J]. JOURNAL OF ANATOMY, 1984, 139 (DEC) : 719 - 719
  • [6] The preovulatory LH surge in the ewe appears to be essentially timed by the hypothalamus
    Ben Said, S.
    Clarke, I. J.
    Lomet, D.
    Caraty, A.
    [J]. REPRODUCTION IN DOMESTIC ANIMALS, 2008, 43 : 142 - 142
  • [7] THE ASSOCIATION OF THE PREOVULATORY SURGE OF LH AND CONCEPTION IN BEEF-CATTLE
    GRIEGER, DM
    ROBERTS, AJ
    REEVES, JJ
    [J]. ANIMAL REPRODUCTION SCIENCE, 1991, 24 (3-4) : 205 - 209
  • [8] Cortisol blocks or delays the preovulatory surge of LH in sheep.
    Daley, CA
    Sakurai, H
    Adams, TE
    [J]. BIOLOGY OF REPRODUCTION, 1997, 56 : 350 - 350
  • [9] LIGHT SYNCHRONIZATION OF THE PREOVULATORY LH-SURGE IN ADRENALECTOMIZED RATS
    BALDWIN, DM
    SAWYER, CH
    [J]. PROCEEDINGS OF THE SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE, 1979, 161 (03): : 295 - 298
  • [10] ASSESSING THE PREOVULATORY LH SURGE WITH A 3-HOUR RADIOIMMUNOASSAY
    LEMAY, A
    DUBOIS, R
    GAGNON, P
    [J]. JOURNAL OF REPRODUCTIVE MEDICINE, 1983, 28 (06) : 402 - 406