POLYMORPHISM OF MITOCHONDRIAL-DNA IN RUSSIAN POPULATION OF RUSSIA

Restriction enzyme fragment patterns in the D-loop and deletion-insertion polymorphism in the V non-coding region of human mitochondrial DNA (mtDNA) were analysed in a Russian population using the polymerase chain reaction. Polymorphisms were detected and mtDNA classified into 26 types using eight enzymes - AvaII, BamHI, EcoRV, KpnI, HaeIII, RsaI, Cfr13I, Sau3AI and Asian specific deletion and insertion. The allele and mitotype frequencies were determined. The data obtained for Russian population and the literature data are comparatively studied.